Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.68 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.68 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.68 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | PLK1 | P53350 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30568369 | 0.90 | ALDH1A1 (0.61) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL2654731 | 0.90 | ALDH1A1 (0.61) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL29805021 | 0.87 | CYP3A4 (0.68) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL20477136 | 0.87 | ALDH1A1 (0.58) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL29804806 | 0.87 | ALDH1A1 (0.58) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL1531127 | 0.87 | CYP3A4 (0.68) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL10440577 | 0.84 | ALDH1A1 (0.59) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL23273179 | 0.82 | MAPT (0.57) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL9316398 | 0.81 | GPR35 (0.66) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL994270 | 0.81 | ALDH1A1 (0.66) | ALDH1A1CYP3A4TSHRTDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0180057-B1 | PROCESS FOR THE PREPARATION OF HALO AROMATIC COMPOUNDS | OCCIDENTAL CHEMICAL CORPORATION (US) | 1989-08-09 | — | — | EP | claimed |
| US-4590315-A | Process for the preparation of halo aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1986-05-20 | — | — | US | claimed |
| EP-0180057-A1 | Process for the preparation of halo aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1986-05-07 | — | — | EP | claimed |
| US-20170283787-A1 | METHOD FOR NON-ENZYMATIC COMBINATION OF NUCLEIC ACID CHAINS | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2017-10-05 | — | — | US | disclosed |
| EP-3187584-A1 | METHOD FOR NON-ENZYMATIC COMBINATION OF NUCLEIC ACID CHAINS | Japan Science and Technology Agency (JP) | 2017-07-05 | — | — | EP | disclosed |
| US-20050107372-A1 | 2-(Quinolonyl)-fused heterocycles as androgen receptor modulators | LANTER JAMES C (US) | 2005-05-19 | — | — | US | disclosed |
| US-6858621-B2 | 2-(quinolonyl)-fused heterocycles as androgen receptor modulators | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2005-02-22 | — | — | US | disclosed |
| EP-1501835-A2 | 2-(QUINOLONYL)-FUSED HETEROCYCLES AS ANDROGEN RECEPTOR MODULATORS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2005-02-02 | — | — | EP | disclosed |
| US-20040014743-A1 | 2-(Quinolonyl)-fused heterocycles as androgen receptor modulators | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-01-22 | — | — | US | disclosed |
| WO-2003090672-A2 | 2-(QUINOLONYL)-FUSED HETEROCYCLES AS ANDROGEN RECEPTOR MODULATORS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2003-11-06 | — | — | WO | disclosed |
| EP-0738713-B1 | Process for the preparation of pesticidal 1-(chloroaryl)heterocyclic compounds | RHONE POULENC AGROCHIMIE (FR) | 2000-02-09 | — | — | EP | disclosed |
| EP-0270964-B1 | PROCESS FOR OBTAINING SUBSTITUTED FLUOROBENZENES | BAYER AG (DE) | 1992-07-08 | — | — | EP | disclosed |
| US-4868347-A | SOLVENT EXTRACTION | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-19 | — | — | US | disclosed |
| EP-0180057-B1 | PROCESS FOR THE PREPARATION OF HALO AROMATIC COMPOUNDS | OCCIDENTAL CHEMICAL CORPORATION (US) | 1989-08-09 | — | — | EP | disclosed |
| EP-0289036-A1 | Preparation of 3-chloro-4,5-difluorobenzotrifluoride | OCCIDENTAL CHEMICAL CORPORATION (US) | 1988-11-02 | — | — | EP | disclosed |
| EP-0270964-A2 | Process for obtaining substituted fluorobenzenes | BAYER AG (DE) | 1988-06-15 | — | — | EP | disclosed |
| US-4590315-A | Process for the preparation of halo aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1986-05-20 | — | — | US | disclosed |
| US-4590315-A | Process for the preparation of halo aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1986-05-20 | — | — | US | disclosed |
| EP-0180057-A1 | Process for the preparation of halo aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1986-05-07 | — | — | EP | disclosed |
| EP-0180057-A1 | Process for the preparation of halo aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1986-05-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014743-A1 | 2-(Quinolonyl)-fused heterocycles as androgen receptor modulators | AR, NR5A1, ESRRA | ALDH1A1 708/4885CYP3A4 295/4885TSHR 401/4885 |
| US-20170283787-A1 | METHOD FOR NON-ENZYMATIC COMBINATION OF NUCLEIC ACID CHAINS | RNGTT, POLRMT, DNTT | ALDH1A1 1261/4885CYP3A4 1474/4885TSHR 2392/4885 |
| US-20050107372-A1 | 2-(Quinolonyl)-fused heterocycles as androgen receptor modulators | AR, NR5A1, CYP19A1 | ALDH1A1 886/4885CYP3A4 334/4885TSHR 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.