Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9998849 | 1.00 | TSHR (0.56) | TSHRALDH1A1CYP3A4RECQLHSD17B10 | |
| SCHEMBL30072759 | 0.87 | MAPT (0.51) | TSHRALDH1A1CYP3A4RECQLHSD17B10 | |
| SCHEMBL18956859 | 0.87 | MAPT (0.51) | TSHRALDH1A1CYP3A4RECQLHSD17B10 | |
| SCHEMBL9998742 | 0.80 | TDP1 (0.48) | TSHRALDH1A1CYP3A4RECQLHSD17B10 | |
| SCHEMBL8031393 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CYP3A4MAPTMEN1LMNA | |
| SCHEMBL21885660 | 0.79 | GPR35 (0.56) | TSHRALDH1A1CYP3A4HSD17B10SMN1; SMN2 | |
| SCHEMBL18607548 | 0.79 | VCAM1 (0.51) | TSHRMAPTMAPK1TDP1 | |
| SCHEMBL8041974 | 0.79 | MAPT (0.58) | TSHRALDH1A1CYP3A4RECQLMAPT | |
| SCHEMBL18607708 | 0.79 | ALDH1A1 (0.51) | TSHRALDH1A1CYP3A4SMN1; SMN2MAPT | |
| SCHEMBL14676672 | 0.79 | HCAR3 (0.54) | ALDH1A1RECQLSMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114042070-A | Compounds as neuronal histamine receptor-3 antagonists and uses thereof | 凯瑞康宁生物工程（武汉）有限公司 | 2022-02-15 | — | — | CN | disclosed |