Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024342 | 0.76 | MAOA (0.32) | MAOA | |
| SCHEMBL8022221 | 0.70 | MAOA (0.34) | MAOA | |
| SCHEMBL8028673 | 0.67 | MAOA (0.45) | MAOA | |
| SCHEMBL8024341 | 0.66 | MAOA (0.33) | MAOA | |
| SCHEMBL8026464 | 0.62 | MAOA (0.44) | MAOA | |
| SCHEMBL8021988 | 0.61 | KMT2A (0.51) | MAOA | |
| SCHEMBL25460455 | 0.61 | MAOA (0.38) | MAOA | |
| SCHEMBL15096141 | 0.61 | MAOA (0.38) | MAOA | |
| SCHEMBL25450533 | 0.58 | MAOA (0.40) | MAOA | |
| SCHEMBL2041555 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095253-A1 | 6-HALO-PYRAZOLO[1, 5-A]PYRIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR (MGLUR) MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-08-06 | — | — | WO | disclosed |