Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026464 | 0.81 | MAOA (0.44) | MAOAASIC3 | |
| SCHEMBL8028086 | 0.77 | MAOA (0.41) | MAOAASIC3 | |
| SCHEMBL2845448 | 0.71 | KDM4E (0.38) | PNMTMEN1TSHRCYP2C19RAB9A | |
| SCHEMBL22044650 | 0.70 | KMT2A (0.51) | MAOAKMT2A | |
| SCHEMBL8021988 | 0.70 | KMT2A (0.51) | MAOAKMT2A | |
| SCHEMBL8023486 | 0.67 | MAOA (0.33) | MAOA | |
| SCHEMBL15161703 | 0.67 | MAOA (0.66) | MAOAASIC3 | |
| SCHEMBL10513171 | 0.66 | PNMT (0.31) | PNMT | |
| SCHEMBL1011216 | 0.66 | PNMT (0.44) | MAOAPNMTTSHR | |
| SCHEMBL14906789 | 0.66 | PNMT (0.37) | PNMTMEN1TSHRCYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095253-A1 | 6-HALO-PYRAZOLO[1, 5-A]PYRIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR (MGLUR) MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-08-06 | — | — | WO | disclosed |