SCHEMBL8026464

SCHEMBL8026464

CC1c2cc(F)sc2CCN1C

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.44
ASIC3 Q9UHC3 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8028673 0.81 MAOA (0.45) MAOAASIC3
SCHEMBL22688406 0.80 L3MBTL1 (0.33)
SCHEMBL8028086 0.79 MAOA (0.41) MAOAASIC3
SCHEMBL22044650 0.69 KMT2A (0.51) MAOA
SCHEMBL8021988 0.69 KMT2A (0.51) MAOA
SCHEMBL8024342 0.68 MAOA (0.32) MAOA
SCHEMBL8034457 0.68 MAOA (0.64) MAOAASIC3
SCHEMBL1861697 0.67 MAOA (0.42) MAOA
SCHEMBL21236170 0.67 MAOA (0.42) MAOA
SCHEMBL8029002 0.66 MAOA (0.56) MAOAASIC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009095253-A1 6-HALO-PYRAZOLO[1, 5-A]PYRIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR (MGLUR) MODULATORS MERZ PHARMA GMBH & CO. KGAA (DE) 2009-08-06 WO disclosed