Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | METAP1 | P53582 | 2/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8615141 | 0.99 | ALDH1A1 (0.41) | ALDH1A1METAP1DDB1CRBNHTR6 | |
| SCHEMBL8009231 | 0.87 | METAP1 (0.38) | METAP1MEN1KMT2AGAALMNA | |
| Hydrochloric Acid SCHEMBL8615828 | 0.86 | METAP1 (0.40) | METAP1GAALMNA | |
| SCHEMBL8025758 | 0.86 | METAP1 (0.38) | METAP1HTR6 | |
| Hydrochloric Acid SCHEMBL8616461 | 0.85 | METAP1 (0.39) | METAP1 | |
| SCHEMBL24969105 | 0.80 | ALDH1A1 (0.47) | ALDH1A1METAP1CRBNHTR6MEN1 | |
| SCHEMBL4665306 | 0.77 | OPRM1 (0.45) | METAP1HTR6MEN1KMT2AHRH3 | |
| SCHEMBL24969443 | 0.76 | USP2 (0.40) | ALDH1A1METAP1DDB1CRBNHTR6 | |
| SCHEMBL11777020 | 0.75 | DDB1 (0.45) | DDB1CRBNGBA1KMT2A | |
| SCHEMBL6929499 | 0.74 | L3MBTL1 (0.47) | ALDH1A1MEN1KMT2AGAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273952-B2 | Substituted C-cyclohexylmethylamine derivatives | GRUENENTHAL GMBH (DE) | 2007-09-25 | — | — | US | disclosed |
| EP-0780369-B1 | 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol derivatives as pharmaceutical agents | GRUENENTHAL GMBH (DE) | 2000-01-19 | — | — | EP | disclosed |
| EP-0780369-A1 | 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol derivatives as pharmaceutical agents | Grünenthal GmbH (DE) | 1997-06-25 | — | — | EP | disclosed |