Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035709 | 0.89 | GPR35 (0.45) | CNR2KMT2AMEN1RXFP1ALDH1A1 | |
| SCHEMBL4768199 | 0.83 | GAA (0.41) | KMT2AMEN1ALDH1A1GAAHPGD | |
| SCHEMBL31104508 | 0.82 | MAPT (0.50) | KMT2AMEN1ALDH1A1GAAHPGD | |
| SCHEMBL3601292 | 0.82 | KDM4E (0.52) | KMT2AMEN1ALDH1A1GAAHPGD | |
| SCHEMBL11959263 | 0.82 | MAPT (0.50) | KMT2AMEN1ALDH1A1GAAHPGD | |
| SCHEMBL10318265 | 0.77 | ALDH1A1 (0.50) | LCKALDH1A1GAAHPGDPOLB | |
| SCHEMBL16318447 | 0.77 | KDM4E (0.52) | LCKKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL2114318 | 0.77 | KMT2A (0.61) | CNR2KMT2AMEN1RXFP1ALDH1A1 | |
| SCHEMBL145260 | 0.76 | ALDH1A1 (0.51) | KMT2AMEN1RXFP1ALDH1A1GAA | |
| SCHEMBL27297 | 0.75 | P2RX7 (0.48) | KMT2ARXFP1ALDH1A1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0987250-A1 | INDOLE DICARBOXYLIC ACID DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2000-03-22 | — | — | EP | disclosed |