Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 9/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710710 | 0.89 | MAOA (0.48) | — | |
| SCHEMBL7704865 | 0.87 | SIGMAR1 (0.41) | SIGMAR1GRM2MEN1KMT2AF10 | |
| SCHEMBL6397247 | 0.85 | MAOA (0.48) | SIGMAR1F10 | |
| SCHEMBL6397251 | 0.85 | MAOA (0.48) | SIGMAR1F10 | |
| SCHEMBL7704866 | 0.83 | GRM2 (0.41) | SIGMAR1GRM2F10 | |
| SCHEMBL6765247 | 0.80 | MAOA (0.45) | SIGMAR1NAMPTF10 | |
| SCHEMBL7028110 | 0.78 | MAOA (0.47) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7024216 | 0.76 | MAOA (0.45) | GRM2ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL8013254 | 0.76 | GRM2 (0.42) | SIGMAR1GRM2F10 | |
| SCHEMBL7153924 | 0.76 | GRM2 (0.42) | SIGMAR1GRM2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166056-A | Phenyloxazolidinones having a C-C bond to 4-8 membered heterocyclic rings | PHARMACIA (US) | 2000-12-26 | — | — | US | disclosed |