Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 13/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7704865 | 0.85 | SIGMAR1 (0.41) | GRM2SIGMAR1F10 | |
| SCHEMBL7520237 | 0.84 | F10 (0.49) | F10 | |
| SCHEMBL8024149 | 0.83 | SIGMAR1 (0.43) | GRM2SIGMAR1F10 | |
| SCHEMBL8024076 | 0.78 | GRM2 (0.43) | GRM2F10 | |
| SCHEMBL8013254 | 0.76 | GRM2 (0.42) | GRM2SIGMAR1F10 | |
| SCHEMBL7153924 | 0.76 | GRM2 (0.42) | GRM2SIGMAR1F10 | |
| SCHEMBL12665391 | 0.75 | SIGMAR1 (0.47) | GRM2SIGMAR1F10 | |
| SCHEMBL8646551 | 0.74 | MAOA (0.46) | F10 | |
| SCHEMBL3567689 | 0.74 | GRM2 (0.47) | GRM2F10 | |
| SCHEMBL3567695 | 0.74 | GRM2 (0.47) | GRM2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365751-B1 | ACTIVE AGAINST GRAM-POSITIVE BACTERIA, IN PARTICULAR, AGAINST STRAINS RESISTANT TO VANCOMYCIN, AMINOGLYCOSIDES AND PENCILLINS AND DERIVATIVES; NONTOXIC | ZENECA LTD. (GB) | 2002-04-02 | — | — | US | disclosed |