Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 12/20 | 0.48 |
| ▸ | FAAH | O00519 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2496082 | 0.82 | MGLL (0.42) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL88581 | 0.76 | CASP3 (0.48) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL10743946 | 0.76 | MGLL (0.46) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL23716871 | 0.74 | MGLL (0.44) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL2463763 | 0.74 | MGLL (0.56) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL21170285 | 0.72 | MGLL (0.38) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL822301 | 0.72 | MGLL (0.42) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL1955696 | 0.72 | MGLL (0.42) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL6537077 | 0.72 | MGLL (0.48) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL9181540 | 0.72 | MGLL (0.48) | MGLLFAAHALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12514926-B2 | Splicing modulator antibody-drug conjugates and methods of use | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2026-01-06 | — | — | US | disclosed |
| US-20250135017-A1 | SPLICING MODULATOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2025-05-01 | — | — | US | disclosed |
| CN-119405832-A | Splice modulating antibody-drug conjugates and methods of use thereof | 卫材R&D管理有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-119405834-A | Splice modulating antibody-drug conjugates and methods of use thereof | 卫材R&D管理有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-119405831-A | Splice modulating antibody-drug conjugates and methods of use thereof | 卫材R&D管理有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-119405833-A | Splice modulating antibody-drug conjugates and methods of use thereof | 卫材R&D管理有限公司 | 2025-02-11 | — | — | CN | disclosed |
| US-12172986-B2 | Splicing modulator antibody-drug conjugates and methods of use | EISAI R&D MANAGEMENT CO., LTD (JP) | 2024-12-24 | — | — | US | disclosed |
| CN-112218663-B | Splice modulating antibody-drug conjugates and methods of use thereof | 卫材R&D管理有限公司 | 2024-11-15 | — | — | CN | disclosed |
| US-20240360108-A1 | SPLICING MODULATOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2024-10-31 | — | — | US | disclosed |
| US-20240252670-A1 | ANTIBODY DRUG CONJUGATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Beijing Synthetic Vaccine Biosciences Co., Ltd. (CN) | 2024-08-01 | — | — | US | disclosed |
| EP-1447099-B1 | Antineoplastic polyethylene conjugates of cytostatic compounds and pharmaceuticals comprising same | KRATZ FELIX (DE) | 2008-01-09 | — | — | EP | disclosed |
| EP-1447099-A2 | Antineoplastic polyethylene conjugates of cytostatic compounds and pharmaceuticals comprising same | Kratz, Felix (DE) | 2004-08-18 | — | — | EP | disclosed |
| EP-0934081-B1 | ANTINEOPLASTIC CONJUGATES OF ALBUMIN | KRATZ FELIX (DE) | 2004-06-09 | — | — | EP | disclosed |
| US-6709679-B2 | CONSISTING OF NATIVE OR THIOLATED TRANSFERRIN OR ALBUMIN OR OF POLYETHYLENE GLYCOL WITH ATLEAST ONE MERCAPTAN, HYDROXY OR AMINE GROUP AND CYTOSTATIC COMPOUNDS DERIVED THROUGH MALEINIMIDE OR HYDROXYSUCCINIMIDE ESTER COMPOUNDS | KRATZ FELIX (DE) | 2004-03-23 | — | — | US | disclosed |
| US-20020019343-A1 | Antineoplastic conjugates of transferrin, albumin and polyethylene glycol | KRATZ FELIX (DE) | 2002-02-14 | — | — | US | disclosed |
| US-6310039-B1 | TUMOR-INHIBITING CONJUGATES OF PROTEINS AND POLYMERS CONSISTING OF A SUITABLE CARRIER SYSTEM AND CYTOSTATIC COMPOUNDS | KRATZ FELIX (DE) | 2001-10-30 | — | — | US | disclosed |
| US-4785010-A | AGING RESISTANCE OF HUMANS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | disclosed |
| EP-0124067-B1 | 2-(AMINOALKYL)-PYRROLE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1986-12-17 | — | — | EP | disclosed |
| EP-0124067-A1 | 2-(Aminoalkyl)-pyrrole derivatives, process for their manufacture and their use | CASSELLA Aktiengesellschaft (DE) | 1984-11-07 | — | — | EP | disclosed |
| US-4088489-A | Method for the preparation of relief structures | SIEMENS AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240360108-A1 | SPLICING MODULATOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE | RBM17, RBM22, SF3B1 | MGLL 4600/4885FAAH 4427/4885ALDH1A1 2080/4885 |
| US-20240252670-A1 | ANTIBODY DRUG CONJUGATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | TLR8, TLR7, PDCD1LG2 | MGLL 1666/4885FAAH 3225/4885ALDH1A1 239/4885 |
| US-20020019343-A1 | Antineoplastic conjugates of transferrin, albumin and polyethylene glycol | TFRC, ALB, FOLR1 | MGLL 3432/4885FAAH 1010/4885ALDH1A1 2933/4885 |
| US-12172986-B2 | Splicing modulator antibody-drug conjugates and methods of use | RBM17, RBM22, SF3B1 | MGLL 4600/4885FAAH 4427/4885ALDH1A1 2080/4885 |
| US-20250135017-A1 | SPLICING MODULATOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE | RBM17, SNRPE, HNRNPAB | MGLL 4708/4885FAAH 4513/4885ALDH1A1 2079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.