Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.83 |
| ▸ | LMNA | P02545 | 3/20 | 0.83 |
| ▸ | CA2 | P00918 | 8/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.54 |
| ▸ | CA9 | Q16790 | 4/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Meticrane SCHEMBL49070 | 0.91 | CYP2C9 (1.00) | CYP2C9LMNACA2CA1CA9 | |
| SCHEMBL8030116 | 0.81 | LMNA (0.56) | CYP2C9LMNACA2CA1CA9 | |
| SCHEMBL19754398 | 0.79 | LMNA (0.51) | CYP2C9LMNACA2CA1CA9 | |
| SCHEMBL11929312 | 0.73 | LMNA (0.70) | CYP2C9LMNACA2CA1CA9 | |
| SCHEMBL15047725 | 0.73 | LMNA (0.46) | CYP2C9LMNACA2CA1CA9 | |
| SCHEMBL11925202 | 0.71 | LMNA (0.67) | CYP2C9LMNACA2KDM4EALDH1A1 | |
| SCHEMBL8024515 | 0.70 | CA2 (1.00) | CYP2C9LMNACA2CA1CA9 | |
| SCHEMBL8029327 | 0.70 | CA2 (0.76) | CYP2C9LMNACA2CA1CA9 | |
| SCHEMBL11511279 | 0.68 | KDM4E (0.52) | CYP2C9LMNACA2CA1CA9 | |
| SCHEMBL28827972 | 0.66 | ALDH1A1 (0.50) | CYP2C9LMNACA2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000063202-A2 | BENZO[b] THIOPHENE SULFONAMIDE-1, 1-DIOXIDE DERIVATIVES AND THEIR USE AS ANTINEOPLASTIC AGENTS | UNIVERSIDAD PUBLICA DE NAVARRA (ES) | 2000-10-26 | — | — | WO | disclosed |