Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 8/20 | 0.33 |
| ▸ | STAT3 | P40763 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036313 | 0.82 | MAOA (0.40) | ALOX15CA12CA1CA2CA9 | |
| SCHEMBL8034589 | 0.82 | RORC (0.42) | ALOX15CA12CA1CA2CA9 | |
| SCHEMBL8034546 | 0.82 | RXRA (0.36) | KDM1ACYP2C9TSHR | |
| SCHEMBL8055080 | 0.72 | GPBAR1 (0.35) | KDM1A | |
| SCHEMBL29388368 | 0.66 | CA12 (0.45) | ALOX15CA12CA1CA2CA9 | |
| SCHEMBL17864531 | 0.66 | CA12 (0.45) | ALOX15CA12CA1CA2CA9 | |
| SCHEMBL109451 | 0.66 | CA1 (0.61) | ALOX15CA12CA1CA2CA9 | |
| SCHEMBL20437077 | 0.66 | CA12 (0.47) | ALOX15CA12CA1CA2CA9 | |
| SCHEMBL23866225 | 0.65 | NOTUM (0.56) | ALOX15CA12CA1CA2CA9 | |
| SCHEMBL24619902 | 0.65 | CA12 (0.41) | ALOX15CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6159973-A | Aromatic amides, their preparation process, the compositions containing them and their use as pesticides | HOECHST SCHERING AGREVO S.A. (FR) | 2000-12-12 | — | — | US | disclosed |
| US-6013837-A | E.G.,4-(2-(3,4,5-TRICHLORO PHENYL) 1-FLUOROCYCLOPROPYL)-N-(2-METHYL PHENYL)BENZAMIDE; PARTICULAR USE AGAINST ARTHROPODS, HELMINTHS AND MOLLUSCS; INSECTICIDES; ACARICIDES; NEMATICIDES; PHOTOSTABILITY; NONTOXIC TO MAMMALS | HOECHST MARION ROUSSEL (FR) | 2000-01-11 | — | — | US | disclosed |