Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 9/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 9/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8060105 | 0.80 | TSHR (0.35) | — | |
| SCHEMBL8038471 | 0.79 | NPC1 (0.46) | ALDH1A1 | |
| SCHEMBL8042055 | 0.78 | S1PR4 (0.40) | — | |
| SCHEMBL8034546 | 0.77 | RXRA (0.36) | KDM1ARCOR1 | |
| SCHEMBL8057744 | 0.75 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL8055091 | 0.74 | TSHR (0.46) | GPBAR1ALDH1A1 | |
| SCHEMBL8034314 | 0.72 | NPSR1 (0.47) | GPBAR1 | |
| SCHEMBL8463202 | 0.71 | MAPT (0.43) | ALDH1A1 | |
| SCHEMBL8036387 | 0.67 | — | — | |
| SCHEMBL3807892 | 0.67 | ALDH1A1 (0.51) | HSD17B1HSD17B2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805795-A1 | NOVEL AROMATIC AMIDES, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS PESTICIDES | Hoechst Schering AgrEvo S.A. (FR) | 1997-11-12 | — | — | EP | claimed |
| WO-1996022965-A1 | NOVEL AROMATIC AMIDES, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS PESTICIDES | HOECHST SCHERING AGREVO S.A. (FR) | 1996-08-01 | — | — | WO | claimed |
| US-6013837-A | E.G.,4-(2-(3,4,5-TRICHLORO PHENYL) 1-FLUOROCYCLOPROPYL)-N-(2-METHYL PHENYL)BENZAMIDE; PARTICULAR USE AGAINST ARTHROPODS, HELMINTHS AND MOLLUSCS; INSECTICIDES; ACARICIDES; NEMATICIDES; PHOTOSTABILITY; NONTOXIC TO MAMMALS | HOECHST MARION ROUSSEL (FR) | 2000-01-11 | — | — | US | disclosed |
| EP-0805795-A1 | NOVEL AROMATIC AMIDES, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS PESTICIDES | Hoechst Schering AgrEvo S.A. (FR) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022965-A1 | NOVEL AROMATIC AMIDES, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS PESTICIDES | HOECHST SCHERING AGREVO S.A. (FR) | 1996-08-01 | — | — | WO | disclosed |