SCHEMBL8025486

SCHEMBL8025486

CCCC(C#N)(CCO)C(N)=O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MCL1 Q07820 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1341188 0.92 MCL1 (0.37) LMNAHSD17B10MCL1
SCHEMBL8809994 0.85 FDPS (0.34) LMNAHSD17B10MCL1
SCHEMBL3108109 0.74 ALDH1A1 (0.35) MCL1
SCHEMBL4734754 0.73 MCL1 (0.34) MCL1
Water SCHEMBL31084442 0.73 MCL1 (0.34) MCL1
SCHEMBL27989962 0.72 ALDH1A1 (0.31)
SCHEMBL1341469 0.71 MEN1 (0.38) MCL1
SCHEMBL28015047 0.71 MCL1 (0.33) MCL1
SCHEMBL3542104 0.69 ALDH1A1 (0.32) MCL1
Nitric Acid SCHEMBL14721077 0.69 CA5A (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6143848-A BY DEGENERATIVE IODINE TRANSFER; RESULTANT POLYMERS HAVE LOW POLYDISPERSITY AND PREDETERMINED MOLECULAR WEIGHT; USEFUL AS REACTIVE INTERMEDIATES IN CONDENSATION POLYMERIZATION, CHAIN POLYMERIZATION AND HETEROGENEOUS POLYMERIZATION REACTIONS THE B.F.GOODRICH COMPANY (US) 2000-11-07 US claimed
US-6143848-A BY DEGENERATIVE IODINE TRANSFER; RESULTANT POLYMERS HAVE LOW POLYDISPERSITY AND PREDETERMINED MOLECULAR WEIGHT; USEFUL AS REACTIVE INTERMEDIATES IN CONDENSATION POLYMERIZATION, CHAIN POLYMERIZATION AND HETEROGENEOUS POLYMERIZATION REACTIONS THE B.F.GOODRICH COMPANY (US) 2000-11-07 US disclosed
EP-0947527-A1 Waterborne block copolymers and process for making the same THE B.F. GOODRICH COMPANY (US) 1999-10-06 EP disclosed
WO-1999020659-A1 END-FUNCTIONALIZED POLYMERS BY CONTROLLED FREE-RADICAL POLYMERIZATION PROCESS AND POLYMERS MADE THEREFROM THE B.F. GOODRICH COMPANY (US) 1999-04-29 WO disclosed