Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.64 |
| ▸ | CCR8 | P51685 | 3/20 | 0.64 |
| ▸ | CCR5 | P51681 | 2/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | METAP2 | P50579 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8025640 | 0.90 | CCR1 (0.73) | CCR1CCR8CCR5HDAC6METAP2 | |
| SCHEMBL23030927 | 0.81 | CCR1 (0.42) | CCR1CCR8CCR5HDAC6METAP2 | |
| SCHEMBL17776912 | 0.81 | CCR1 (0.59) | CCR1CCR8CCR5HDAC6METAP2 | |
| SCHEMBL10032237 | 0.81 | CCR1 (0.59) | CCR1CCR8CCR5HDAC6METAP2 | |
| SCHEMBL14473534 | 0.81 | KDM4E (0.67) | CCR1CCR8CCR5HDAC6METAP2 | |
| SCHEMBL13051887 | 0.81 | CCR1 (0.59) | CCR1CCR8METAP2CYP2A6CYP3A4 | |
| SCHEMBL12681427 | 0.81 | CCR1 (0.59) | CCR1CCR8CCR5HDAC6METAP2 | |
| SCHEMBL16189350 | 0.81 | CCR1 (0.59) | CCR1CCR8CCR5HDAC6METAP2 | |
| Abametapir SCHEMBL351152 | 0.80 | CCR1 (1.00) | CCR1CCR8CCR5HDAC6METAP2 | |
| Abametapir SCHEMBL29374261 | 0.80 | CCR1 (1.00) | CCR1CCR8CCR5HDAC6METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10454042-B2 | Organic electroluminescence device | UDC IRELAND LIMITED (IE) | 2019-10-22 | — | — | US | disclosed |
| US-10030013-B2 | Heteroaryl compounds as IRAK inhibitors and uses thereof | MERCK PATENT GMBH (DE) | 2018-07-24 | — | — | US | disclosed |
| US-20180002327-A1 | HETEROARYL COMPOUNDS AS IRAK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2018-01-04 | — | — | US | disclosed |
| US-9790221-B2 | Heteroaryl compounds as IRAK inhibitors and uses thereof | MERCK PATENT GMBH (DE) | 2017-10-17 | — | — | US | disclosed |
| US-9755159-B2 | Organic materials for OLEDs | UNIVERSAL DISPLAY CORPORATION (US) | 2017-09-05 | — | — | US | disclosed |
| US-9755159-B2 | Organic materials for OLEDs | UNIVERSAL DISPLAY CORPORATION (US) | 2017-09-05 | — | — | US | disclosed |
| US-9502656-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2016-11-22 | — | — | US | disclosed |
| US-9502656-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2016-11-22 | — | — | US | disclosed |
| US-20160260910-A1 | Organic Electroluminescent Device; A Charge Transporting Material For The Organic Electroluminescent Device; And A Luminescent Device, A Display Device And A Lighting System Using The Organic Electroluminescent Device | UDC IRELAND LTD (IE) | 2016-09-08 | — | — | US | disclosed |
| US-20160260910-A1 | Organic Electroluminescent Device; A Charge Transporting Material For The Organic Electroluminescent Device; And A Luminescent Device, A Display Device And A Lighting System Using The Organic Electroluminescent Device | UDC IRELAND LTD (IE) | 2016-09-08 | — | — | US | disclosed |
| US-20120091445-A1 | COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE | CHEIL INDUSTRIES, INC. (KR) | 2012-04-19 | — | — | US | disclosed |
| US-20120091445-A1 | COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE | CHEIL INDUSTRIES, INC. (KR) | 2012-04-19 | — | — | US | disclosed |
| US-7993760-B2 | Compound for use in organic electroluminescent device and organic electroluminescent device | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2011-08-09 | — | — | US | disclosed |
| US-7993760-B2 | Compound for use in organic electroluminescent device and organic electroluminescent device | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2011-08-09 | — | — | US | disclosed |
| US-20110118411-A1 | POLYMERIC COMPOUND HAVING RESIDUE OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-05-19 | — | — | US | disclosed |
| US-20110118411-A1 | POLYMERIC COMPOUND HAVING RESIDUE OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-05-19 | — | — | US | disclosed |
| EP-2275469-A1 | POLYMERIC COMPOUND HAVING RESIDUE OF NITROGENATED HETEROCYCLIC COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2011-01-19 | — | — | EP | disclosed |
| US-20090302742-A1 | Compound for Use in Organic Electroluminescent Device and Organic Electroluminescent Device | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2009-12-10 | — | — | US | disclosed |
| US-20090021146-A1 | ORGANIC COMPOUND, CHARGE TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE | PIONEER CORPORATION (JP) | 2009-01-22 | — | — | US | disclosed |
| WO-2000053642-A1 | CONTROLLED (CO)POLYMERISATION WITH N-HETEROCYCLES METAL COMPLEX SYSTEMS | SCHUBERT ULRICH S (DE) | 2000-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10030013-B2 | Heteroaryl compounds as IRAK inhibitors and uses thereof | IRAK2, IRAK3, IRAK1 | CCR1 620/4885CCR8 1092/4885CCR5 618/4885 |
| US-20090021146-A1 | ORGANIC COMPOUND, CHARGE TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE | SLC25A21, SLCO2A1, OCIAD2 | CCR1 569/4885CCR8 2694/4885CCR5 2793/4885 |
| US-20090302742-A1 | Compound for Use in Organic Electroluminescent Device and Organic Electroluminescent Device | LAGE3, ICMT, PPOX | CCR1 3138/4885CCR8 4189/4885CCR5 934/4885 |
| US-20180002327-A1 | HETEROARYL COMPOUNDS AS IRAK INHIBITORS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | CCR1 620/4885CCR8 1092/4885CCR5 618/4885 |
| US-20120091445-A1 | COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE | OR51E2, AOX1, OR10J3 | CCR1 1720/4885CCR8 2460/4885CCR5 1637/4885 |
| US-10454042-B2 | Organic electroluminescence device | EML4, ELOC, ORC3 | CCR1 3292/4885CCR8 3738/4885CCR5 1641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.