Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CD74 | P04233 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | USP9X | Q93008 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL8025677 | 1.00 | KMT2A (0.40) | KMT2AKDM4EMEN1NPC1POLB | |
| Lysine SCHEMBL8035593 | 0.89 | GSR (0.38) | KMT2AKDM4EMEN1NPC1POLB | |
| Lysine SCHEMBL8035596 | 0.89 | GSR (0.38) | KMT2AKDM4EMEN1NPC1POLB | |
| Cyclohexylamine SCHEMBL8035113 | 0.88 | KMT2A (0.44) | KMT2AKDM4EMEN1NPC1POLB | |
| Cyclohexylamine SCHEMBL7792748 | 0.87 | KDM4E (0.49) | KMT2AKDM4EMEN1NPC1POLB | |
| Cyclohexylamine SCHEMBL8037307 | 0.84 | KIF11 (0.37) | KMT2AKDM4EMEN1NPC1RAB9A | |
| Cyclohexylamine SCHEMBL8037314 | 0.84 | KIF11 (0.37) | KMT2AKDM4EMEN1NPC1RAB9A | |
| 2-Naphthaldehyde SCHEMBL8035927 | 0.79 | GRIK1 (0.46) | KMT2AMEN1LMNAKIF11PPARG | |
| 2-Naphthaldehyde SCHEMBL8035922 | 0.79 | GRIK1 (0.46) | KMT2AMEN1LMNAKIF11PPARG | |
| Benzaldehyde SCHEMBL8035694 | 0.78 | KIF11 (0.42) | KMT2AMEN1KIF11PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |