Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | PPARA | Q07869 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 3/20 | 0.33 |
| ▸ | F2R | P25116 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL8037314 | 1.00 | KIF11 (0.37) | KIF11PPARGPPARATSHRGRM5 | |
| Lysine SCHEMBL8035744 | 0.89 | GSR (0.40) | KIF11PPARGPPARATSHRKMT2A | |
| Lysine SCHEMBL8035739 | 0.89 | GSR (0.40) | KIF11PPARGPPARATSHRKMT2A | |
| Cyclohexylamine SCHEMBL8039390 | 0.87 | TSHR (0.36) | PPARGPPARATSHRGRM5F2R | |
| Cyclohexylamine SCHEMBL8025677 | 0.84 | KMT2A (0.40) | KIF11PPARGPPARANPC1RAB9A | |
| Cyclohexylamine SCHEMBL8025671 | 0.84 | KMT2A (0.40) | KIF11PPARGPPARANPC1RAB9A | |
| Benzaldehyde SCHEMBL8035694 | 0.78 | KIF11 (0.42) | KIF11PPARGPPARAALDH1A1MEN1 | |
| Cyclohexylamine SCHEMBL8039053 | 0.76 | GRIK1 (0.46) | KIF11PPARGPPARAALDH1A1KDM4E | |
| Cyclohexylamine SCHEMBL8039051 | 0.76 | GRIK1 (0.46) | KIF11PPARGPPARAALDH1A1KDM4E | |
| 3-Hydroxybenzaldehyde SCHEMBL8039109 | 0.76 | KYNU (0.40) | KIF11PPARGPPARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |