Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.46 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 4/20 | 0.38 |
| ▸ | METAP1 | P53582 | 3/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTR1E | P28566 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Naphthaldehyde SCHEMBL8035922 | 1.00 | GRIK1 (0.46) | GRIK1GRIK2GRIK3PPARGPPARA | |
| 2-Naphthaldehyde SCHEMBL8025531 | 0.88 | GRIK1 (0.43) | GRIK1GRIK2GRIK3PPARGPPARA | |
| 2-Naphthaldehyde SCHEMBL8025528 | 0.88 | GRIK1 (0.43) | GRIK1GRIK2GRIK3PPARGPPARA | |
| 2-Naphthaldehyde SCHEMBL7797967 | 0.88 | GRIK1 (0.39) | GRIK1GRIK2GRIK3PPARGPPARA | |
| Benzaldehyde SCHEMBL8035694 | 0.88 | KIF11 (0.42) | GRIK1GRIK2PPARGPPARAKIF11 | |
| Cyclohexylamine SCHEMBL8041275 | 0.85 | LTA4H (0.40) | PPARGPPARAEPHX1KIF11METAP2 | |
| Cyclohexylamine SCHEMBL8041272 | 0.85 | LTA4H (0.40) | PPARGPPARAEPHX1KIF11METAP2 | |
| 2-Naphthaldehyde SCHEMBL7797994 | 0.85 | RAB9A (0.41) | EPHX1LMNA | |
| Cyclohexylamine SCHEMBL8037292 | 0.83 | EPOR (0.41) | GRIK1GRIK2PPARGPPARAMEN1 | |
| Cyclohexylamine SCHEMBL8037294 | 0.83 | EPOR (0.41) | GRIK1GRIK2PPARGPPARAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |