Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A5 | Q15758 | 4/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EPOR | P19235 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-(Aminomethyl)Phenol SCHEMBL8025681 | 1.00 | SLC1A5 (0.45) | SLC1A5GRIK1GRIK2BACE1NPC1 | |
| 2-(Aminomethyl)Phenol SCHEMBL7798293 | 0.90 | NPC1 (0.46) | SLC1A5BACE1NPC1RAB9ATDP1 | |
| Lysine SCHEMBL7802021 | 0.90 | SLC1A5 (0.46) | SLC1A5GRIK1GRIK2BACE1NPC1 | |
| Lysine SCHEMBL7802016 | 0.90 | SLC1A5 (0.46) | SLC1A5GRIK1GRIK2BACE1NPC1 | |
| 2-(Aminomethyl)Phenol SCHEMBL8035202 | 0.87 | KMO (0.44) | SLC1A5NPC1RAB9AEPORMAOA | |
| 2-(Aminomethyl)Phenol SCHEMBL8035206 | 0.87 | KMO (0.44) | SLC1A5NPC1RAB9AEPORMAOA | |
| 2-(Aminomethyl)Phenol SCHEMBL7801377 | 0.83 | EPOR (0.45) | BACE1NPC1RAB9AEPORMAOA | |
| Diaminopropanoic Acid SCHEMBL8035562 | 0.82 | GRIK1 (0.59) | SLC1A5GRIK1GRIK2NPC1RAB9A | |
| Diaminopropanoic Acid SCHEMBL8035556 | 0.82 | GRIK1 (0.59) | SLC1A5GRIK1GRIK2NPC1RAB9A | |
| Cyclohexylamine SCHEMBL8041423 | 0.80 | GRIK1 (0.43) | SLC1A5GRIK1GRIK2BACE1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |