Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.39 |
| ▸ | EPOR | P19235 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL8041427 | 1.00 | GRIK1 (0.43) | GRIK1GRIK2NPC1RAB9ATDP1 | |
| Cyclohexylamine SCHEMBL8037294 | 0.93 | EPOR (0.41) | GRIK1GRIK2EPORMEN1KMT2A | |
| Cyclohexylamine SCHEMBL8037292 | 0.93 | EPOR (0.41) | GRIK1GRIK2EPORMEN1KMT2A | |
| Cyclohexylamine SCHEMBL7801463 | 0.90 | NPC1 (0.46) | NPC1RAB9ATDP1CTSLCTSS | |
| Lysine SCHEMBL8035746 | 0.90 | DPP8 (0.41) | GRIK1GRIK2NPC1RAB9ATDP1 | |
| Lysine SCHEMBL8035745 | 0.90 | DPP8 (0.41) | GRIK1GRIK2NPC1RAB9ATDP1 | |
| Cyclohexylamine SCHEMBL7800354 | 0.87 | NPC1 (0.50) | NPC1RAB9ATDP1MTNR1AMTNR1B | |
| Cyclohexylamine SCHEMBL8035833 | 0.87 | KMO (0.41) | GRIK1GRIK2NPC1RAB9AKMT2A | |
| Cyclohexylamine SCHEMBL8035834 | 0.87 | KMO (0.41) | GRIK1GRIK2NPC1RAB9AKMT2A | |
| Cyclohexylamine SCHEMBL8041275 | 0.87 | LTA4H (0.40) | PPARGPPARAFFAR1NPY5RKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |