SCHEMBL8486182

SCHEMBL8486182

C/C=C(\Oc1cccc(I)c1)C(=O)OC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
APP P05067 1/20 0.40
PARP1 P09874 1/20 0.39
RAB9A P51151 5/20 0.39
NPC1 O15118 4/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.39
HTT P42858 1/20 0.39
RXFP1 Q9HBX9 1/20 0.38
ABCG2 Q9UNQ0 1/20 0.37
NLRP3 Q96P20 1/20 0.37
TAS1R3 Q7RTX0 1/20 0.37
TAS1R1 Q7RTX1 1/20 0.37
MTNR1A P48039 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8026284 0.83 NPC1 (0.54) CES2CES1MEN1KMT2AESR1
SCHEMBL7695022 0.83 LMNA (0.57) MEN1KMT2ARAB9ANPC1SMN1; SMN2
SCHEMBL7688667 0.78 MTNR1A (0.44) MEN1KMT2ASMN1; SMN2ALDH1A1HTT
SCHEMBL1513774 0.74 LMNA (0.63) MEN1KMT2ARAB9ANPC1SMN1; SMN2
SCHEMBL8022472 0.74 CTBP2 (0.41) MEN1KMT2ASMN1; SMN2ALDH1A1HTT
SCHEMBL8022000 0.73 NPC1 (0.49) CES2CES1MEN1KMT2ARAB9A
SCHEMBL8021996 0.73 NPC1 (0.49) CES2CES1MEN1KMT2ARAB9A
SCHEMBL25876124 0.72 ELANE (0.53) CES2CES1MEN1KMT2AESR1
SCHEMBL8026280 0.72 NPC1 (0.48) CES2CES1MEN1KMT2AESR1
SCHEMBL8026283 0.72 NPC1 (0.48) CES2CES1MEN1KMT2AESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5985919-A INSECTICIDES AND FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 1999-11-16 US disclosed