Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7603792 | 0.81 | THRB (0.39) | LMNACA12CA1CA2CA3 | |
| SCHEMBL15415598 | 0.73 | ALDH1A1 (0.42) | CYP2D6LMNAALDH1A1KMT2AMAPT | |
| SCHEMBL11556911 | 0.70 | LMNA (0.53) | CYP2D6LMNACA12CA1CA2 | |
| SCHEMBL1878246 | 0.69 | LMNA (0.69) | CYP2D6LMNACA12CA1CA2 | |
| SCHEMBL21313417 | 0.69 | LMNA (0.69) | CYP2D6LMNACA12CA1CA2 | |
| SCHEMBL8353244 | 0.69 | LMNA (0.69) | CYP2D6LMNACA12CA1CA2 | |
| SCHEMBL28238942 | 0.69 | CYP3A4 (0.36) | CYP2D6LMNAALDH1A1KMT2AMAPT | |
| SCHEMBL7342413 | 0.68 | LMNA (0.50) | CYP2D6LMNACA12CA1CA2 | |
| SCHEMBL11024710 | 0.68 | LMNA (0.46) | CYP2D6LMNACA12CA1CA2 | |
| SCHEMBL18874588 | 0.68 | LMNA (0.50) | CYP2D6LMNACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976738-A2 | Propylene ureas and the process for their preparation | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-02-02 | — | — | EP | disclosed |