Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026320 | 0.81 | CYP2D6 (0.38) | LMNAKMT2AALDH1A1CA12CA1 | |
| SCHEMBL7566446 | 0.79 | MMP1 (0.33) | THRBLMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL7573611 | 0.71 | MEN1 (0.31) | LMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL28977958 | 0.68 | LMNA (0.47) | THRBLMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL19975025 | 0.67 | LMNA (0.42) | THRBLMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL8089482 | 0.66 | PER2 (0.37) | LMNAALDH1A1CA12CA1CA2 | |
| SCHEMBL11778854 | 0.66 | — | — | |
| SCHEMBL3789749 | 0.65 | LMNA (0.69) | THRBLMNAKMT2AALDH1A1MEN1 | |
| Cyclohexanone SCHEMBL4579788 | 0.64 | THRB (0.46) | THRBLMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL840430 | 0.64 | MEN1 (0.40) | KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976738-B1 | Process for the preparation of propylene ureas | DAINIPPON INK & CHEMICALS (JP) | 2002-12-04 | — | — | EP | disclosed |