Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030002 | 0.86 | MAOA (0.47) | MAOAPRCPCHRNB2CHRNA4 | |
| SCHEMBL14877517 | 0.82 | SIGMAR1 (0.35) | SIGMAR1CHRNB2CHRNA4 | |
| SCHEMBL8028105 | 0.76 | MAOA (0.49) | MAOA | |
| SCHEMBL8277213 | 0.76 | TRPM8 (0.36) | — | |
| SCHEMBL8023498 | 0.75 | CYP11B1 (0.51) | — | |
| SCHEMBL8023492 | 0.74 | PRCP (0.61) | MAOAPRCP | |
| SCHEMBL8021507 | 0.74 | PRCP (0.61) | MAOAPRCP | |
| SCHEMBL811761 | 0.74 | PRCP (0.61) | MAOAPRCP | |
| SCHEMBL8025234 | 0.73 | MAOA (0.49) | MAOAPRCP | |
| SCHEMBL8023501 | 0.72 | CYP11B2 (0.50) | MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095253-A1 | 6-HALO-PYRAZOLO[1, 5-A]PYRIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR (MGLUR) MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-08-06 | — | — | WO | disclosed |