SCHEMBL8026499

SCHEMBL8026499

O=C1N=C([AsH2])c2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
CDC25B P30305 2/20 0.39
MAOA P21397 3/20 0.38
APAF1 O14727 2/20 0.38
TDP2 O95551 2/20 0.38
POLB P06746 2/20 0.38
S100A4 P26447 2/20 0.38
MAPK1 P28482 2/20 0.38
RECQL P46063 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CES2 O00748 1/20 0.38
TERT O14746 1/20 0.38
NPC1 O15118 1/20 0.38
PLIN1 O60240 1/20 0.38
S1PR4 O95977 1/20 0.38
LMNA P02545 1/20 0.38
PLA2G1B P04054 1/20 0.38
BCHE P06276 1/20 0.38
PTPRC P08575 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL879050 0.70 CDC25B (0.39) MEN1KMT2ACDC25BMAOAAPAF1
SCHEMBL29492985 0.70 CDC25B (0.39) MEN1KMT2ACDC25BMAOAAPAF1
Phthalimide SCHEMBL1388700 0.70 APAF1 (0.44) MEN1KMT2ACDC25BMAOAAPAF1
SCHEMBL2026326 0.70 MEN1 (0.39) MEN1KMT2ACDC25BMAOAAPAF1
SCHEMBL3697487 0.70 MEN1 (0.39) MEN1KMT2ACDC25BMAOAAPAF1
SCHEMBL31131321 0.70 LMNA (0.45) MEN1KMT2ACDC25BMAOAAPAF1
SCHEMBL2359460 0.70 IDO1 (0.44) MEN1KMT2ACDC25BMAOAAPAF1
SCHEMBL9152647 0.70 KMT2A (0.35) MEN1KMT2ACDC25BMAOAAPAF1
SCHEMBL29714477 0.69 MEN1 (0.50) MEN1KMT2ACDC25BMAOAAPAF1
SCHEMBL19888 0.69 MEN1 (0.50) MEN1KMT2ACDC25BMAOAAPAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1056433-A1 DYEING METHOD USING A SPECIFIC ACTIVE METHYLENE COMPOUND AND A COMPOUND SELECTED AMONG A SPECIFIC ALDEHYDE, A SPECIFIC KETONE, A QUINONE AND A DI-IMINO-ISOINDOLINE OR 3-AMINO-ISOINDOLONE DERIVATIVE L'OREAL (FR) 2000-12-06 EP claimed
WO-2000038638-A1 DYEING METHOD USING A SPECIFIC ACTIVE METHYLENE COMPOUND AND A COMPOUND SELECTED AMONG A SPECIFIC ALDEHYDE, A SPECIFIC KETONE, A QUINONE AND A DI-IMINO-ISOINDOLINE OR 3-AMINO-ISOINDOLONE DERIVATIVE L'OREAL (FR) 2000-07-06 WO claimed