Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.38 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29492985 | 1.00 | CDC25B (0.39) | CDC25BMEN1KMT2AMAOALMNA | |
| SCHEMBL2072302 | 0.76 | CDC25B (0.39) | CDC25BMEN1KMT2AMAOALMNA | |
| SCHEMBL3697487 | 0.75 | MEN1 (0.39) | CDC25BMEN1KMT2AMAOALMNA | |
| SCHEMBL17671420 | 0.75 | MAOA (0.48) | MAOAMAPTMAOBALDH1A1ELANE | |
| SCHEMBL14455164 | 0.74 | MAPK1 (0.44) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL30423822 | 0.73 | CA1 (0.44) | MEN1KMT2ASMN1; SMN2RAB9AMAPK1 | |
| SCHEMBL18786963 | 0.72 | ESR2 (0.48) | MAOAMAOBTTR | |
| SCHEMBL20529361 | 0.72 | S100A4 (0.48) | MEN1KMT2AMAPTMAPK1KDM4E | |
| SCHEMBL17141524 | 0.72 | S100A4 (0.48) | POLBCES1PTPRCS100A4RECQL | |
| SCHEMBL19124739 | 0.72 | S100A4 (0.48) | LMNAMAPK1CES1S100A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11884628-B2 | Method for synthesizing lactam derivatives without use of catalyst | GUIZHOU UNIVERSITY (CN) | 2024-01-30 | — | — | US | claimed |
| WO-2022253252-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS HPK1 INHIBITORS | SILEXON BIOTECH CO., LTD. (CN) | 2022-12-08 | — | — | WO | claimed |
| US-20220177429-A1 | METHOD FOR SYNTHESIZING LACTAM DERIVATIVES WITHOUT USE OF CATALYST | GUIZHOU UNIVERSITY (CN) | 2022-06-09 | — | — | US | claimed |
| WO-2020228170-A1 | CATALYST-FREE SYNTHESIS METHOD FOR LACTAM DERIVATIVE | 贵州大学 | 2020-11-19 | — | — | WO | claimed |
| EP-1784399-B1 | PYRIMIDINE DERIVATIVES | NOVARTIS AG (CH) | 2011-06-15 | — | — | EP | claimed |
| JP-4674236-B2 | — | — | 2011-04-20 | — | — | JP | claimed |
| US-7910585-B2 | Pyrimidine derivatives | NOVARTIS AG (CH) | 2011-03-22 | — | — | US | claimed |
| US-20080293708-A1 | Pyrimidine Derivatives | NOVARTIS AG (CH) | 2008-11-27 | — | — | US | claimed |
| JP-2008510765-A | — | — | 2008-04-10 | — | — | JP | claimed |
| CN-101006079-A | Pyrimidine derivatives | NOVARTIS AG (CH) | 2007-07-25 | — | — | CN | claimed |
| EP-1784399-A2 | PYRIMIDINE DERIVATIVES | Novartis AG (CH) | 2007-05-16 | — | — | EP | claimed |
| WO-2006021457-A2 | PYRIMIDINE DERIVATIVES | NOVARTIS AG (CH) | 2006-03-02 | — | — | WO | claimed |
| US-20260109696-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | Interdict Bio, Inc. (US) | 2026-04-23 | — | — | US | disclosed |
| US-12590078-B2 | — | — | 2026-03-31 | — | — | US | disclosed |
| US-20260078130-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | SIRONAX LTD (KY) | 2026-03-19 | — | — | US | disclosed |
| US-20260078116-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | Interdict Bio, Inc. (US) | 2026-03-19 | — | — | US | disclosed |
| EP-1496838-A2 | SUBSTITUTED AMIDES | Merck & Co., Inc. (US) | 2005-01-19 | — | — | EP | disclosed |
| WO-2004058145-A2 | SUBSTITUTED AMIDES | MERCK & CO., INC. (US) | 2004-07-15 | — | — | WO | disclosed |
| US-20040058820-A1 | Central nervous system disorders; psychological disorders; antiinflammatory agents; multiple sclerosis | MERCK SHARP & DOHME LLC | 2004-03-25 | — | — | US | disclosed |
| WO-2003077847-A2 | SUBSTITUTED AMIDES | MERCK & CO., INC. (US) | 2003-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078130-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | NAMPT, NNMT, SARM1 | CDC25B 3747/4885MEN1 2008/4885KMT2A 2737/4885 |
| US-11884628-B2 | Method for synthesizing lactam derivatives without use of catalyst | COASY, SI, NAAA | CDC25B 2596/4885MEN1 1464/4885KMT2A 321/4885 |
| US-12590078-B2 | — | ADRM1, USP19, USP1 | CDC25B 2904/4885MEN1 3638/4885KMT2A 2342/4885 |
| US-20040058820-A1 | Central nervous system disorders; psychological disorders; antiinflammatory agents; multiple sclerosis | CNR1, CNR2, MAG | CDC25B 4081/4885MEN1 178/4885KMT2A 3170/4885 |
| US-20220177429-A1 | METHOD FOR SYNTHESIZING LACTAM DERIVATIVES WITHOUT USE OF CATALYST | COASY, SI, NAAA | CDC25B 2596/4885MEN1 1464/4885KMT2A 321/4885 |
| US-20260078116-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | MYC, KRAS, MCL1 | CDC25B 459/4885MEN1 1248/4885KMT2A 2402/4885 |
| US-20260109696-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | KRAS, MYC, NRAS | CDC25B 598/4885MEN1 1555/4885KMT2A 1898/4885 |
| US-20080293708-A1 | Pyrimidine Derivatives | DPYD, TYMP, TYMS | CDC25B 408/4885MEN1 4489/4885KMT2A 3238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.