Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27115962 | 0.98 | PTGS2 (0.47) | PTGS2AKR1C3AKR1C2PTGS1AKR1B10 | |
| SCHEMBL21373998 | 0.91 | PTGS2 (0.45) | PTGS2AKR1C3AKR1C2PTGS1AKR1B10 | |
| SCHEMBL21374000 | 0.91 | PTGS2 (0.45) | PTGS2AKR1C3AKR1C2PTGS1AKR1B10 | |
| SCHEMBL10018722 | 0.90 | AKR1C3 (0.54) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL14365640 | 0.90 | AKR1C3 (0.54) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL19912967 | 0.90 | PTGS2 (0.50) | PTGS2AKR1C3AKR1C2PTGS1AKR1B10 | |
| SCHEMBL21374093 | 0.89 | PTGS2 (0.46) | PTGS2AKR1C3AKR1C2PTGS1AKR1B10 | |
| SCHEMBL803426 | 0.86 | PDE3B (0.48) | PTGS2AKR1C3AKR1C2PTGS1AKR1B10 | |
| SCHEMBL26548051 | 0.85 | PTGS2 (0.42) | PTGS2AKR1C3AKR1C2PTGS1AKR1B10 | |
| SCHEMBL12889477 | 0.84 | NFE2L2 (0.47) | PTGS2AKR1C3AKR1C2PTGS1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043781-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2024-07-23 | — | — | US | disclosed |
| US-11781069-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2023-10-10 | — | — | US | disclosed |
| US-11718791-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2023-08-08 | — | — | US | disclosed |
| US-11702597-B2 | Azo dye | MERCK PATENT GMBH (DE) | 2023-07-18 | — | — | US | disclosed |
| US-11685863-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2023-06-27 | — | — | US | disclosed |
| US-11667845-B2 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2023-06-06 | — | — | US | disclosed |
| US-11655417-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2023-05-23 | — | — | US | disclosed |
| US-20180201837-A1 | Method of Reducing ODF Mura in Polymer Stabilised Liquid Crystal Displays | MERCK PATENT GMBH (DE) | 2018-07-19 | — | — | US | disclosed |
| US-20180195003-A1 | PROCESS FOR THE STABILISATION OF LIQUID CRYSTAL MEDIA | MERCK PATENT GMBH (DE) | 2018-07-12 | — | — | US | disclosed |
| US-20180179446-A1 | LIQUID CRYSTAL MEDIUM CONTAINING POLYMERISABLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2018-06-28 | — | — | US | disclosed |
| US-20130114034-A1 | LIQUID CRYSTALLINE MEDIA AND LIQUID CRYSTAL DISPLAYS WITH A POLYMER-STABILIZED HOMEOTROPIC ORIENTATION | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-05-09 | — | — | US | disclosed |
| US-20120327357-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL MEDIA AND LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-12-27 | — | — | US | disclosed |
| US-20120224124-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID CRYSTAL DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-09-06 | — | — | US | disclosed |
| US-20120182516-A1 | POLYMERIZABLE COMPOUNDS AND THEIR USE IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-07-19 | — | — | US | disclosed |
| US-20120162595-A1 | LIQUID-CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-06-28 | — | — | US | disclosed |
| US-20120069289-A1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-03-22 | — | — | US | disclosed |
| US-20110261311-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL MEDIA AND LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-10-27 | — | — | US | disclosed |
| US-20110255048-A1 | LIQUID-CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2011-10-20 | — | — | US | disclosed |
| US-20110051049-A1 | LIQUID-CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT (DE) | 2011-03-03 | — | — | US | disclosed |
| US-20100272925-A1 | LIQUID-CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT (DE) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718791-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | VCL, ILK, LCP1 | PTGS2 4474/4885AKR1C3 4067/4885AKR1C2 4097/4885 |
| US-20110255048-A1 | LIQUID-CRYSTAL DISPLAY | KLK3, BPHL, LPXN | PTGS2 4417/4885AKR1C3 3538/4885AKR1C2 3146/4885 |
| US-11667845-B2 | Liquid crystalline medium | NEFM, CCNI, MYT1 | PTGS2 1498/4885AKR1C3 4108/4885AKR1C2 4449/4885 |
| US-20120182516-A1 | POLYMERIZABLE COMPOUNDS AND THEIR USE IN LIQUID-CRYSTAL DISPLAYS | VCL, LPXN, ACP3 | PTGS2 3677/4885AKR1C3 3619/4885AKR1C2 3402/4885 |
| US-20100272925-A1 | LIQUID-CRYSTAL DISPLAY | KLK3, BPHL, LPXN | PTGS2 4197/4885AKR1C3 2930/4885AKR1C2 2659/4885 |
| US-11685863-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | LPXN, VCL, LCP1 | PTGS2 4446/4885AKR1C3 3514/4885AKR1C2 3386/4885 |
| US-20120224124-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID CRYSTAL DISPLAYS | VCL, LPXN, LCP1 | PTGS2 3932/4885AKR1C3 3609/4885AKR1C2 3467/4885 |
| US-20110051049-A1 | LIQUID-CRYSTAL DISPLAY | VCL, LPXN, ACP3 | PTGS2 4406/4885AKR1C3 3796/4885AKR1C2 3523/4885 |
| US-20120327357-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL MEDIA AND LIQUID-CRYSTAL DISPLAYS | LPXN, VCL, MAP1LC3C | PTGS2 2941/4885AKR1C3 4105/4885AKR1C2 3815/4885 |
| US-20110261311-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL MEDIA AND LIQUID-CRYSTAL DISPLAYS | LPXN, MAP1LC3C, VCL | PTGS2 2773/4885AKR1C3 4148/4885AKR1C2 3845/4885 |
| US-20120069289-A1 | LIQUID CRYSTAL DISPLAY | LPXN, VCL, ACP3 | PTGS2 4411/4885AKR1C3 3318/4885AKR1C2 3116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.