Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 4/20 | 0.32 |
| ▸ | CNR2 | P34972 | 4/20 | 0.32 |
| ▸ | KRAS | P01116 | 1/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024509 | 0.80 | EGFR (0.40) | EGFRMEN1KMT2ACNR1CNR2 | |
| SCHEMBL8024922 | 0.79 | EGFR (0.42) | EGFRMEN1KMT2ACNR1CNR2 | |
| SCHEMBL8025390 | 0.79 | EGFR (0.42) | EGFRCNR1CNR2KRASSOS1 | |
| SCHEMBL8014129 | 0.77 | EGFR (0.43) | EGFRKRASSOS1RPS6KB1 | |
| SCHEMBL8028223 | 0.75 | GALR3 (0.55) | EGFRKRASSOS1GALR3NR2F2 | |
| SCHEMBL7173846 | 0.75 | GALR3 (0.55) | EGFRKRASSOS1GALR3NR2F2 | |
| SCHEMBL7173843 | 0.75 | GALR3 (0.55) | EGFRKRASSOS1GALR3NR2F2 | |
| SCHEMBL7173840 | 0.75 | GALR3 (0.55) | EGFRKRASSOS1GALR3NR2F2 | |
| SCHEMBL8024930 | 0.73 | EGFR (0.48) | EGFRCNR1CNR2KRASSOS1 | |
| SCHEMBL8014573 | 0.73 | LMNA (0.47) | EGFRCNR1CNR2KRASSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543402-B1 | Aralkylaminopyrimidine derivative, method for preparing the same and composition for controlling noxious organisms | UBE INDUSTRIES (JP) | 2000-03-01 | — | — | EP | claimed |
| US-5280025-A | Aralkylaminopyrimidine derivative, and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1994-01-18 | — | — | US | claimed |
| EP-0543402-A1 | Aralkylaminopyrimidine derivative, method for preparing the same and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1993-05-26 | — | — | EP | claimed |