Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTR1E | P28566 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KRAS | P01116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8014129 | 0.89 | EGFR (0.43) | EGFRPDE5AKRASSOS1P2RX3 | |
| SCHEMBL8025127 | 0.83 | EGFR (0.46) | EGFRPDE5ASMN1; SMN2KRASSOS1 | |
| SCHEMBL8024509 | 0.83 | EGFR (0.40) | EGFRMAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8025390 | 0.81 | EGFR (0.42) | EGFRKRASSOS1CNR1CNR2 | |
| SCHEMBL9728955 | 0.80 | EGFR (0.43) | EGFRPDE2AKRASSOS1CNR1 | |
| SCHEMBL8026893 | 0.79 | EGFR (0.37) | EGFRMEN1KMT2AKRASSOS1 | |
| SCHEMBL9729028 | 0.77 | EGFR (0.41) | EGFRKRASSOS1CNR1CNR2 | |
| SCHEMBL8024930 | 0.77 | EGFR (0.48) | EGFRALDH1A1KRASSOS1CNR1 | |
| SCHEMBL8014573 | 0.77 | LMNA (0.47) | EGFRMAPTRAB9ALMNATP53 | |
| SCHEMBL8024317 | 0.76 | EGFR (0.49) | EGFRRAB9ASMN1; SMN2LMNACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543402-B1 | Aralkylaminopyrimidine derivative, method for preparing the same and composition for controlling noxious organisms | UBE INDUSTRIES (JP) | 2000-03-01 | — | — | EP | claimed |
| US-5280025-A | Aralkylaminopyrimidine derivative, and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1994-01-18 | — | — | US | claimed |
| EP-0543402-A1 | Aralkylaminopyrimidine derivative, method for preparing the same and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1993-05-26 | — | — | EP | claimed |