Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1011527 | 0.73 | NPC1 (0.36) | NPC1RAB9AMAOAMAPTSMN1; SMN2 | |
| SCHEMBL8015297 | 0.72 | DRD3 (0.36) | MAOA | |
| SCHEMBL8022070 | 0.69 | MAOA (0.41) | MAOA | |
| SCHEMBL12930243 | 0.67 | NPC1 (0.57) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL8030417 | 0.65 | MEN1 (0.44) | MAOA | |
| SCHEMBL7978723 | 0.65 | GID4 (0.44) | MAOASMN1; SMN2LMNA | |
| SCHEMBL8027387 | 0.65 | GID4 (0.44) | MAOA | |
| SCHEMBL8028688 | 0.65 | ADRA2A (0.50) | MAOA | |
| SCHEMBL16762220 | 0.63 | DYRK1A (0.47) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL8027390 | 0.63 | MAOA (0.53) | MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095253-A1 | 6-HALO-PYRAZOLO[1, 5-A]PYRIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR (MGLUR) MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-08-06 | — | — | WO | disclosed |