Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039720 | 0.90 | TSHR (0.67) | ALDH1A1TSHRTDP1KDM4EHTT | |
| SCHEMBL8041218 | 0.87 | MEN1 (0.49) | ALDH1A1TSHRTDP1KDM4EHTT | |
| SCHEMBL8039700 | 0.86 | ALDH1A1 (0.49) | ALDH1A1TSHRTDP1KDM4EHTT | |
| SCHEMBL8038282 | 0.85 | PLK1 (0.50) | ALDH1A1TSHRTDP1KDM4EHTT | |
| SCHEMBL8037897 | 0.84 | CTSV (0.52) | KMT2AMEN1LMNAHCAR2NPC1 | |
| SCHEMBL8044213 | 0.82 | MEN1 (0.50) | ALDH1A1TSHRTDP1KDM4EHTT | |
| SCHEMBL8039687 | 0.81 | SRD5A1 (0.43) | ALDH1A1TSHRTDP1KDM4EHTT | |
| SCHEMBL8041262 | 0.81 | TSHR (0.64) | ALDH1A1TSHRTDP1KDM4EHTT | |
| SCHEMBL8039714 | 0.80 | ABCC1 (0.45) | ALDH1A1TSHRTDP1KDM4EHTT | |
| SCHEMBL8039543 | 0.80 | ABCC1 (0.45) | ALDH1A1TSHRTDP1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |