SCHEMBL8028070

SCHEMBL8028070

O=C1CC(=S)NC(=S)N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8660061 0.88
Thiobarbituric SCHEMBL31059040 0.85 GSK3A (0.38)
Thiobarbituric SCHEMBL16027 0.85
Thiobarbituric SCHEMBL8216351 0.82 GSK3A (0.36)
Thiobarbituric SCHEMBL2344775 0.82 GSK3A (0.36)
Thiobarbituric SCHEMBL2351184 0.82 GSK3A (0.36)
Barbituric Acid SCHEMBL4726594 0.78 ALDH1A1 (0.44)
SCHEMBL1673293 0.78
SCHEMBL14459294 0.74
Thiobarbituric SCHEMBL7714190 0.74 ALDH1A1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120137947-A Alpha-amylase mutant, biological material, catalyst and application 南京大学 2025-06-13 CN disclosed
CN-119662604-A High-temperature-resistant beta-mannase mutant and preparation method thereof 南京大学 2025-03-21 CN disclosed
CN-119634055-A Copper-molybdenum bulk concentrate flotation separation method and combined inhibitor used in same 紫金矿业集团股份有限公司 2025-03-18 CN disclosed
CN-117904079-B Alpha-amylase mutant, gene, vector and preparation method thereof 南京大学 2024-12-10 CN disclosed
CN-117904079-A Alpha-amylase mutant, gene, vector and preparation method thereof 南京大学 2024-04-19 CN disclosed
US-20210227827-A1 METHOD FOR PATHOGENS, MICROORGANISMS, AND PARASITES INACTIVATION NEW YORK BLOOD CENTER, INC. 2021-07-29 US disclosed
WO-2020023881-A1 METHOD FOR PATHOGENS, MICROORGANISMS, AND PARASITES INACTIVATION ZATA PHARMACEUTICALS, INC. (US) 2020-01-30 WO disclosed
US-9725547-B2 Vulcanisable compositions based on epoxy group-containing nitrile rubbers ARLANXEO DEUTSCHLAND GMBH (DE) 2017-08-08 US disclosed
CN-103857738-B Curable compositions based on nitrile rubbers containing epoxy groups LANXESS DEUTSCHLAND GMBH (DE) 2015-08-12 CN disclosed
US-20140378618-A1 VULCANISABLE COMPOSITIONS BASED ON EPOXY GROUP-CONTAINING NITRILE RUBBERS ARLANXEO DEUTSCHLAND GMBH (DE) 2014-12-25 US disclosed
US-5373055-A Melt kneading a polyester and a epoxy-group containing ethylene copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-12-13 US disclosed
US-5334666-A Vulcanizable elastomer composition comprising epoxy group-containing elastomer, organic compound having at least two -C(X)-NH-C(Y)-bonds (X=O or S, Y=O or S), quaternary ammonium or phosphonium salt, and optionally a urea or thiourea compound NIPPON ZEON CO., LTD. (JP) 1994-08-02 US disclosed
EP-0257640-B1 Vulcanizable elastomer composition NIPPON ZEON CO (JP) 1994-03-16 EP disclosed
US-5292825-A Imide or thioimide compound, and phosphine compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-03-08 US disclosed
EP-0480770-A2 Thermoplastic elastomer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-04-15 EP disclosed
EP-0480769-A2 Method for producing impact-resistant polyester resin compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-04-15 EP disclosed
US-5039756-A Vulcanization Systems SUMITOMO CHEMICAL CO., LTD. (JP) 1991-08-13 US disclosed
EP-0416885-A1 Vulcanizable epoxy group-containing elastomer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-03-13 EP disclosed
EP-0400890-A2 Method for producing thermoplastic elastomer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-12-05 EP disclosed
EP-0257640-A2 Vulcanizable elastomer composition NIPPON ZEON CO., LTD. (JP) 1988-03-02 EP disclosed