Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.32 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026464 | 0.79 | MAOA (0.44) | MAOAASIC3 | |
| SCHEMBL8028673 | 0.77 | MAOA (0.45) | MAOAASIC3 | |
| SCHEMBL22458037 | 0.73 | HTR2A (0.30) | — | |
| SCHEMBL1869183 | 0.70 | MAOA (0.39) | MAOA | |
| SCHEMBL22044650 | 0.66 | KMT2A (0.51) | MAOA | |
| SCHEMBL8021988 | 0.66 | KMT2A (0.51) | MAOA | |
| SCHEMBL8021471 | 0.66 | HTR2C (0.52) | MAOAASIC3 | |
| SCHEMBL12969035 | 0.64 | MAOA (0.39) | MAOA | |
| SCHEMBL25801225 | 0.62 | — | — | |
| SCHEMBL8024342 | 0.61 | MAOA (0.32) | MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095253-A1 | 6-HALO-PYRAZOLO[1, 5-A]PYRIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR (MGLUR) MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-08-06 | — | — | WO | disclosed |