Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029828 | 0.98 | KEAP1 (0.37) | KEAP1NFE2L2 | |
| SCHEMBL66869 | 0.80 | KEAP1 (0.45) | KEAP1NFE2L2SSTR4 | |
| SCHEMBL8107590 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL4888357 | 0.76 | ALDH1A1 (0.32) | KEAP1NFE2L2 | |
| SCHEMBL15114535 | 0.73 | MEN1 (0.31) | — | |
| SCHEMBL15114499 | 0.73 | SLC6A3 (0.33) | — | |
| SCHEMBL8187257 | 0.70 | — | — | |
| SCHEMBL29017354 | 0.67 | — | — | |
| SCHEMBL29017357 | 0.67 | — | — | |
| SCHEMBL7919980 | 0.67 | SMN1; SMN2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121241-A | TREATING CARDIOVASCULAR DISORDERS | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2000-09-19 | — | — | US | disclosed |
| EP-0863871-B1 | ANTICOAGULANT PEPTIDE ALDEHYDE DERIVATIVES | GYOGYSZERKUTATO INTEZET (HU) | 2000-03-08 | — | — | EP | disclosed |
| EP-0863871-A1 | ANTICOAGULANT PEPTIDE ALDEHYDE DERIVATIVES | GYOGYSZERKUTATO INTEZET KFT. (HU) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997046523-A1 | ANTICOAGULANT PEPTIDE ALDEHYDE DERIVATIVES | Gyógyszerkutató Intézet Kft. (HU) | 1997-12-11 | — | — | WO | disclosed |