Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | CDC25C | P30307 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038236 | 0.92 | AOC3 (0.40) | KDM4EKMT2AL3MBTL1AOC3CYP2C9 | |
| SCHEMBL12335334 | 0.84 | KDM4E (0.45) | KDM4EKMT2AL3MBTL1AOC3CNR1 | |
| SCHEMBL2326062 | 0.82 | AOC3 (0.39) | KDM4EKMT2AAOC3CYP2C9 | |
| SCHEMBL2326069 | 0.82 | AOC3 (0.39) | KDM4EKMT2AAOC3CYP2C9 | |
| SCHEMBL11567917 | 0.80 | KDM4E (0.49) | KDM4EKMT2AL3MBTL1AOC3CNR1 | |
| SCHEMBL4595927 | 0.79 | THRB (0.44) | THRBTHRATSHRCNR2 | |
| SCHEMBL5450041 | 0.79 | AOC3 (0.36) | KDM4EAOC3CYP2C9 | |
| SCHEMBL8038185 | 0.79 | THRB (0.42) | KDM4EKMT2ATHRBTHRATSHR | |
| SCHEMBL8038199 | 0.78 | THRA (0.43) | KDM4EKMT2AL3MBTL1THRBTHRA | |
| SCHEMBL9572563 | 0.78 | AOC3 (0.43) | KDM4EKMT2AL3MBTL1AOC3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | claimed |
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | disclosed |