Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041640 | 0.93 | TSHR (0.40) | THRATHRBKDM4EKMT2ATSHR | |
| SCHEMBL9450840 | 0.80 | THRB (0.44) | THRATHRBKDM4EKMT2AALDH1A1 | |
| SCHEMBL9491739 | 0.80 | THRB (0.43) | THRATHRBTSHRCNR2HPGD | |
| SCHEMBL10441457 | 0.79 | THRA (0.37) | THRATHRBKDM4EALDH1A1HPGD | |
| SCHEMBL1561008 | 0.78 | ALDH1A1 (0.43) | KDM4EKMT2AL3MBTL1TSHRALDH1A1 | |
| SCHEMBL8028264 | 0.78 | KDM4E (0.42) | THRATHRBKDM4EKMT2AL3MBTL1 | |
| SCHEMBL8041642 | 0.77 | PPARG (0.49) | THRATHRBKDM4EKMT2AL3MBTL1 | |
| SCHEMBL10441454 | 0.77 | L3MBTL1 (0.39) | THRATHRBL3MBTL1TSHRALDH1A1 | |
| SCHEMBL8040122 | 0.76 | THRB (0.45) | THRATHRBTSHRCNR2ALDH1A1 | |
| SCHEMBL27662670 | 0.76 | KDM4E (0.47) | KDM4EKMT2AHTR1BTSHRCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | claimed |
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | disclosed |