Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC37A4 | O43826 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028287 | 0.96 | ALDH1A1 (0.39) | SLC37A4ALDH1A1HSD17B10KDM4EPOLB | |
| SCHEMBL16181833 | 0.85 | TSHR (0.40) | SLC37A4ALDH1A1KDM4ETSHRPPARG | |
| SCHEMBL8038185 | 0.82 | THRB (0.42) | SLC37A4ALDH1A1HSD17B10KDM4EPOLB | |
| SCHEMBL27909025 | 0.81 | ALDH1A1 (0.43) | SLC37A4ALDH1A1POLBTSHRPPARG | |
| Bromide SCHEMBL16166941 | 0.81 | SLC37A4 (0.36) | SLC37A4ALDH1A1KDM4ETSHRPPARG | |
| SCHEMBL4447340 | 0.80 | ALDH1A1 (0.45) | SLC37A4ALDH1A1POLBTSHRPRSS1 | |
| SCHEMBL6446367 | 0.80 | ALDH1A1 (0.45) | SLC37A4ALDH1A1POLBTSHRPRSS1 | |
| SCHEMBL1562513 | 0.80 | ALDH1A1 (0.45) | SLC37A4ALDH1A1POLBTSHRPRSS1 | |
| SCHEMBL28204949 | 0.79 | KDM4E (0.41) | SLC37A4ALDH1A1KDM4ETSHRPPARG | |
| Methacrylic Acid SCHEMBL28345316 | 0.78 | ALDH1A1 (0.43) | SLC37A4ALDH1A1POLBTSHRPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | claimed |
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | disclosed |