Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADA | P00813 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | AMPD3 | Q01432 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029815 | 0.89 | ALDH1A1 (0.43) | MEN1KMT2AADORA3ADORA2AADORA1 | |
| SCHEMBL6137853 | 0.78 | ALDH1A1 (0.46) | MEN1KMT2AADORA3ADORA2AADORA1 | |
| SCHEMBL5950179 | 0.77 | MEN1 (0.46) | MEN1KMT2AADORA3ADORA2AADORA1 | |
| SCHEMBL8018540 | 0.77 | ATIC (0.48) | ADORA1SMN1; SMN2 | |
| SCHEMBL3287568 | 0.75 | ALDH1A1 (0.43) | ADORA3ADORA1ADAKDM4EALDH1A1 | |
| SCHEMBL8028076 | 0.74 | P2RX3 (0.48) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL41683 | 0.73 | KDM4E (0.47) | MEN1KMT2AADORA3ADORA2AADORA1 | |
| SCHEMBL21356432 | 0.73 | PDE2A (0.44) | ADORA3ADORA2AADORA1ADAKDM4E | |
| SCHEMBL3819352 | 0.73 | SLC29A1 (0.47) | ADORA3ADORA2AADORA1ADORA2BTSHR | |
| SCHEMBL8028292 | 0.71 | ADA (0.44) | MEN1KMT2AADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130324-A | HAVING MODIFIED PURINE NUCLEOTIDES; VIRICIDES AGAINST HUMAN IMMUNODEFICIENCY VIRUS AND HUMAN CYTOMEGALOVIRUS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2000-10-10 | — | — | US | disclosed |