Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28931538 | 0.86 | HTT (0.47) | STSHTTKDM1AKLK7FKBP1A | |
| SCHEMBL7382767 | 0.84 | FKBP1A (0.53) | STSKLK7FKBP1AMEN1KMT2A | |
| SCHEMBL31099047 | 0.83 | MEN1 (0.54) | STSMEN1KMT2ALMNAKDM4E | |
| SCHEMBL4696737 | 0.82 | HTT (0.51) | HTTFKBP1AALDH1A1HSD17B10 | |
| SCHEMBL28779720 | 0.80 | USP30 (0.58) | STSKEAP1NFE2L2GPR119LMNA | |
| SCHEMBL6440981 | 0.80 | KLK7 (0.51) | STSKLK7FKBP1AMEN1KMT2A | |
| SCHEMBL28779718 | 0.80 | USP30 (0.58) | STSKEAP1NFE2L2GPR119LMNA | |
| SCHEMBL27978282 | 0.79 | FKBP1A (0.52) | FKBP1AKMT2ALMNAKDM4E | |
| SCHEMBL29424741 | 0.79 | EPHX1 (0.43) | KDM1AFKBP1AMEN1KMT2ALMNA | |
| SCHEMBL5173012 | 0.79 | ALDH1A1 (0.64) | KLK7FKBP1AMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000059498-A1 | PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2000-10-12 | — | — | WO | disclosed |