Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | THPO | P40225 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11557714 | 0.74 | NPC1 (0.45) | GRM5NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL5249356 | 0.70 | FFAR1 (0.66) | GRM5FFAR1FFAR4CYP1A2CYP3A4 | |
| SCHEMBL4285196 | 0.70 | ATM (0.44) | CYP2D6 | |
| SCHEMBL7220481 | 0.69 | L3MBTL1 (0.44) | GRM5NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL11453485 | 0.68 | SMN1; SMN2 (0.42) | NPC1RAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8028571 | 0.68 | GRM5 (0.39) | GRM5NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL10768214 | 0.68 | CYP1A2 (0.64) | GRM5FFAR1FFAR4CYP1A2CYP3A4 | |
| SCHEMBL10798421 | 0.67 | FFAR1 (0.61) | GRM5FFAR1FFAR4NPC1SMN1; SMN2 | |
| SCHEMBL10233436 | 0.66 | CYP1A2 (0.47) | GRM5NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL21894058 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6037367-A | Substituted-pent-4-ynoic acids | SMITHKLINE BEECHAM CORPORATION (US) | 2000-03-14 | — | — | US | claimed |