Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | GLA | P06280 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28273258 | 0.95 | AKR1C3 (0.61) | ALDH1A1GLATDP1POLBL3MBTL1 | |
| SCHEMBL8440119 | 0.91 | HTT (0.67) | ALDH1A1GLATDP1POLBL3MBTL1 | |
| SCHEMBL2710798 | 0.91 | HTT (0.67) | ALDH1A1GLATDP1POLBL3MBTL1 | |
| SCHEMBL6583591 | 0.91 | HTT (0.67) | ALDH1A1GLATDP1POLBL3MBTL1 | |
| SCHEMBL9315389 | 0.87 | ALDH1A1 (0.82) | ALDH1A1GLATDP1POLBL3MBTL1 | |
| SCHEMBL10824895 | 0.87 | AKR1C3 (0.53) | ALDH1A1GLATDP1POLBL3MBTL1 | |
| SCHEMBL10824894 | 0.87 | AKR1C3 (0.53) | ALDH1A1GLATDP1POLBL3MBTL1 | |
| SCHEMBL11377680 | 0.87 | AKR1C3 (0.53) | ALDH1A1GLATDP1POLBL3MBTL1 | |
| SCHEMBL10824896 | 0.87 | AKR1C3 (0.53) | ALDH1A1GLATDP1POLBL3MBTL1 | |
| SCHEMBL11377632 | 0.87 | AKR1C3 (0.53) | ALDH1A1GLATDP1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 427 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106632100-B | Preparation method of antibacterial veterinary drug quinocetone | 杭州洪桥中科基因技术有限公司 | 2020-01-31 | — | — | CN | claimed |
| CN-108358831-A | A kind of polysubstituted carbazole derivates and preparation method thereof | 山东师范大学 | 2018-08-03 | — | — | CN | claimed |
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | claimed |
| US-20080275264-A1 | PROCESS FOR THE PREPARATION OF HALOGENOALKYLDIALKYL CHLOROSILANE | RHODIA CHIMIE (FR) | 2008-11-06 | — | — | US | claimed |
| US-7413579-B2 | Method for dyeing fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-08-19 | — | — | US | claimed |
| EP-1633761-B1 | METHOD OF PREPARING HALOGENOALKYLDIALKYLCHLOROSILANE | RHODIA CHIMIE SA (FR) | 2008-05-07 | — | — | EP | claimed |
| EP-1909913-A1 | METHOD FOR QUICKLY CONCEALING THE ROOTS OF HAIR THAT HAVE GROWN AFTER THE HAIR HAS BEEN DYED | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-04-16 | — | — | EP | claimed |
| US-7300472-B2 | Agents for coloring fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-11-27 | — | — | US | claimed |
| US-20070185344-A1 | Method of preparing halogenoalkyldialkyl chlorosilane | RHODIA CHIMIE (FR) | 2007-08-09 | — | — | US | claimed |
| EP-1789015-A1 | METHOD FOR STYLISHLY CHANGING THE COLOR OF KERATINIC FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-05-30 | — | — | EP | claimed |
| EP-0873743-A2 | Use of benzylidene-ketones for dyeing keratinous fibers | Henkel Kommanditgesellschaft auf Aktien (DE) | 1998-10-28 | — | — | EP | claimed |
| US-5583242-A | VANADYL COMPLEXES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-10 | — | — | US | claimed |
| US-5565491-A | FOR TREATMENT OF DISEASES MARKED BY MALIGNANT PROLIFERATION OF B CELLS, SUCH AS LEUKEMIA AND LYMPHOMAS; ANTICARCINOGENIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-10-15 | — | — | US | claimed |
| EP-0357403-B1 | Substituted beta-diketones | ORION YHTYMAE OY (FI) | 1994-12-14 | — | — | EP | claimed |
| US-5288750-A | Antiulcer agents for gastrointestinal disorders | ORION-YHTYMA OY (FI) | 1994-02-22 | — | — | US | claimed |
| WO-1990002724-A1 | SUBSTITUTED β-DIKETONES | Orion-Yhtymä Oy (FI) | 1990-03-22 | — | — | WO | claimed |
| EP-0357403-A2 | Substituted beta-diketones | ORION-YHTYMÀ OY (FI) | 1990-03-07 | — | — | EP | claimed |
| US-4703099-A | CATALYTICALLY TRIMERIZING ISOCYANATES | THE DOW CHEMICAL COMPANY (US) | 1987-10-27 | — | — | US | claimed |
| US-4632989-A | KETENE AMINAL-OLEFIN REACTION PRODUCT AS CATALYSTS | THE DOW CHEMICAL COMPANY (US) | 1986-12-30 | — | — | US | claimed |
| US-4536490-A | REACTION PRODUCT OF KETENE-AMINAL AND UNSATURATED COMPOUND | THE UPJOHN COMPANY (US) | 1985-08-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185344-A1 | Method of preparing halogenoalkyldialkyl chlorosilane | HACL2, UBE3C, MCCC2 | ALDH1A1 777/4885GLA 4064/4885TDP1 4272/4885 |
| US-20080275264-A1 | PROCESS FOR THE PREPARATION OF HALOGENOALKYLDIALKYL CHLOROSILANE | HDHD5, DDC, HACL2 | ALDH1A1 428/4885GLA 4463/4885TDP1 4449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.