Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | SNCA | P37840 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.49 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030338 | 0.87 | JUN (0.51) | APPKDM4ESMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL8028844 | 0.78 | GRIK1 (0.58) | APPMAPK1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8031858 | 0.78 | JUN (0.52) | APPKDM4ESMN1; SMN2ALDH1A1NFE2L2 | |
| SCHEMBL18569889 | 0.77 | NFE2L2 (0.61) | APPMAPK1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL783249 | 0.76 | APP (0.70) | APPMAPK1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL6320958 | 0.76 | APP (0.70) | APPMAPK1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL6320126 | 0.76 | APP (0.70) | APPMAPK1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8028615 | 0.76 | JUN (0.52) | APPKDM4ESMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL8028618 | 0.76 | JUN (0.52) | APPKDM4ESMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL8029524 | 0.76 | JUN (0.52) | APPKDM4ESMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000063152-A1 | ACETYLATED AND RELATED ANALOGUES OF CHICORIC ACID AS HIV INTEGRASE INHIBITORS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2000-10-26 | — | — | WO | disclosed |