Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 10/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | FABP3 | P05413 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL106656 | 0.97 | BBOX1 (0.58) | BBOX1CA1FFAR3HDAC3HDAC1 | |
| Sebacic Acid SCHEMBL5874500 | 0.94 | BBOX1 (0.56) | BBOX1CA1FFAR3HDAC3HDAC1 | |
| Tetramethylammonium Ion SCHEMBL8438225 | 0.94 | BBOX1 (0.56) | BBOX1CA1FFAR3HDAC3HDAC1 | |
| Glutarate SCHEMBL104188 | 0.91 | BBOX1 (0.58) | BBOX1CA1FFAR3HDAC3HDAC1 | |
| Adipic Acid SCHEMBL613527 | 0.87 | CA1 (0.58) | BBOX1CA1FFAR3HDAC3HDAC1 | |
| Adipic Acid SCHEMBL106658 | 0.87 | LMNA (0.55) | BBOX1CA1FABP3 | |
| Hexanoate SCHEMBL105666 | 0.87 | CA1 (0.68) | BBOX1CA1FABP3 | |
| Adipic Acid SCHEMBL6848399 | 0.85 | BBOX1 (0.72) | BBOX1CA1FFAR3HDAC3HDAC1 | |
| Tetramethylammonium Ion SCHEMBL23754606 | 0.85 | BBOX1 (0.48) | BBOX1CA1FABP3 | |
| Sebacic Acid SCHEMBL5874508 | 0.85 | TSHR (0.57) | BBOX1FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684619-B1 | Ion-conductive polymer electrolyte and electrolytic capacitor using the same | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |