Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9906142 | 0.79 | TSHR (0.57) | TSHRACHETDP1MAPTNPC1 | |
| SCHEMBL10535334 | 0.78 | ESR1 (0.54) | TSHRMAPTNPC1RAB9ACA1 | |
| SCHEMBL27992363 | 0.78 | OGG1 (0.40) | NPC1RAB9ACA1CA2CA9 | |
| SCHEMBL8354799 | 0.77 | TSHR (0.55) | TSHRACHETDP1MAPTNPC1 | |
| SCHEMBL8178159 | 0.77 | TAAR1 (0.46) | TSHRMAPTALDH1A1HDAC1HDAC6 | |
| SCHEMBL18591715 | 0.75 | TSHR (0.52) | TSHRACHETDP1MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL31564741 | 0.75 | TAAR1 (0.44) | MAPTALDH1A1HDAC1HDAC6KMT2A | |
| SCHEMBL18539275 | 0.73 | KIF11 (0.41) | TSHRMAPTRAB9AALDH1A1KIF11 | |
| SCHEMBL20787876 | 0.73 | TSHR (0.44) | TSHRACHETDP1MAPTNPC1 | |
| SCHEMBL8446138 | 0.73 | TSHR (0.44) | TSHRACHETDP1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0868420-B1 | 3-PYRAZOLECARBOXAMIDE DERIVATIVES HAVING CANNABINOID RECEPTOR AFFINITY | SANOFI SYNTHELABO (FR) | 2000-03-29 | — | — | EP | disclosed |