Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 6/20 | 0.41 |
| ▸ | CCR9 | P51686 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3005494 | 0.80 | PTGDR2 (0.47) | ALDH1A1L3MBTL1KDM4EGAAKMO | |
| SCHEMBL10054048 | 0.80 | BRPF1 (0.50) | ALDH1A1BRPF1CNR1KDM4EGAA | |
| SCHEMBL3785498 | 0.80 | SCN7A (0.56) | NTRK1ALDH1A1MAPK1STAT3CCR2 | |
| SCHEMBL2591249 | 0.78 | KDM4E (0.49) | ALDH1A1CCR2KDM4E | |
| SCHEMBL1467597 | 0.78 | CCR2 (0.54) | CCR2KMO | |
| SCHEMBL1251025 | 0.78 | CCR2 (0.47) | ALDH1A1CCR2BRPF1L3MBTL1KDM4E | |
| SCHEMBL7958147 | 0.77 | NTRK1 (0.57) | NTRK1CCR2BRPF1CNR1CCR9 | |
| SCHEMBL16709583 | 0.76 | PTGDR2 (0.50) | ALDH1A1MAPK1STAT3L3MBTL1KDM4E | |
| SCHEMBL3067363 | 0.75 | L3MBTL1 (0.64) | ALDH1A1CCR2L3MBTL1KDM4EMAPT | |
| SCHEMBL27990361 | 0.74 | CCR2 (0.50) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043257-A | ANTICOAGULANT; PYRIDINE SUBSTITUTED INDAZOLE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-03-28 | — | — | US | disclosed |
| US-5886191-A | ANTICOAGULANTS | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-03-23 | — | — | US | disclosed |