Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | IGF1R | P08069 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035719 | 0.90 | LTA4H (0.63) | LTA4HALDH1A1KDM4ESIGMAR1ATM | |
| SCHEMBL8029920 | 0.90 | LTA4H (0.65) | LTA4HKDM4ESIGMAR1ATMIGF1R | |
| SCHEMBL8020078 | 0.86 | LTA4H (0.65) | LTA4HALDH1A1KDM4ESIGMAR1ATM | |
| SCHEMBL8020087 | 0.85 | MAPK1 (0.60) | LTA4HALDH1A1KDM4ESIGMAR1ATM | |
| SCHEMBL8035796 | 0.84 | SIGMAR1 (0.68) | LTA4HALDH1A1KDM4ESIGMAR1FAAH | |
| SCHEMBL8020088 | 0.83 | LTA4H (0.57) | LTA4HALDH1A1KDM4ESIGMAR1ATM | |
| SCHEMBL8029900 | 0.83 | LTA4H (0.57) | LTA4HSIGMAR1ATMFAAHLMNA | |
| SCHEMBL8029605 | 0.81 | MEN1 (0.58) | ALDH1A1KDM4EFAAHHTTHRH3 | |
| SCHEMBL8033271 | 0.81 | KDM4E (0.48) | LTA4HALDH1A1KDM4EATMIGF1R | |
| SCHEMBL8035768 | 0.79 | SIGMAR1 (0.57) | LTA4HALDH1A1KDM4ESIGMAR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702010-B1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-03-15 | — | — | EP | disclosed |
| US-5668138-A | AFFINITY FOR SIGMA RECEPTORS, CENTRAL NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-09-16 | — | — | US | disclosed |
| EP-0702010-A1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-03-20 | — | — | EP | disclosed |