Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020088 | 0.90 | LTA4H (0.57) | MAPK1PKMLTA4HSMN1; SMN2LMNA | |
| SCHEMBL8029920 | 0.89 | LTA4H (0.65) | LTA4HLMNAHTTKDM4EMEN1 | |
| SCHEMBL8020078 | 0.88 | LTA4H (0.65) | MAPK1LTA4HSMN1; SMN2LMNAMAPT | |
| SCHEMBL8035719 | 0.86 | LTA4H (0.63) | LTA4HKDM4EALDH1A1FAAHATM | |
| SCHEMBL8029621 | 0.85 | LTA4H (0.61) | LTA4HSMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL8035796 | 0.83 | SIGMAR1 (0.68) | MAPK1PKMLTA4HSMN1; SMN2LMNA | |
| SCHEMBL8029900 | 0.82 | LTA4H (0.57) | MAPK1LTA4HLMNAMAPTL3MBTL1 | |
| SCHEMBL8029611 | 0.82 | PKM (0.67) | MAPK1PKMSMN1; SMN2LMNAHTT | |
| SCHEMBL8035768 | 0.81 | SIGMAR1 (0.57) | LTA4HSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL8029940 | 0.77 | SIGMAR1 (0.52) | LTA4HSMN1; SMN2HTTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702010-B1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-03-15 | — | — | EP | disclosed |
| US-5668138-A | AFFINITY FOR SIGMA RECEPTORS, CENTRAL NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-09-16 | — | — | US | disclosed |
| EP-0702010-A1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-03-20 | — | — | EP | disclosed |