Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028186 | 0.82 | KDM4E (0.36) | TP53MAPT | |
| SCHEMBL29383802 | 0.80 | PTPN1 (0.38) | — | |
| SCHEMBL8031445 | 0.80 | PTPN1 (0.38) | — | |
| SCHEMBL6843532 | 0.80 | GHSR (0.36) | MAPT | |
| SCHEMBL8024372 | 0.77 | MAOB (0.50) | LMNAMAPTSLC10A2 | |
| SCHEMBL21586026 | 0.75 | SLC10A2 (0.31) | SLC10A2 | |
| SCHEMBL21585955 | 0.75 | LMNA (0.34) | LMNAMAPT | |
| SCHEMBL29381681 | 0.75 | PTPN1 (0.39) | — | |
| SCHEMBL22286617 | 0.72 | PTPN1 (0.34) | — | |
| SCHEMBL29728473 | 0.72 | PTPN1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792268-B1 | HYPOLIPIDEMIC BENZOTHIAZEPINES | WELLCOME FOUND (GB) | 2000-02-23 | — | — | EP | disclosed |
| US-5998400-A | Hypolipidemic benzothiazepines | GLAXO WELLCOME INC. (US) | 1999-12-07 | — | — | US | disclosed |
| WO-1996016051-A1 | HYPOLIPIDEMIC BENZOTHIAZEPINES | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-05-30 | — | — | WO | disclosed |