Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 12/20 | 0.61 |
| ▸ | BRD1 | O95696 | 9/20 | 0.60 |
| ▸ | BRPF3 | Q9ULD4 | 6/20 | 0.60 |
| ▸ | BRD4 | O60885 | 4/20 | 0.60 |
| ▸ | BRD9 | Q9H8M2 | 4/20 | 0.60 |
| ▸ | BRD7 | Q9NPI1 | 2/20 | 0.60 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.56 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8016504 | 0.82 | BRPF1 (0.52) | BRPF1BRD1BRPF3BRD4BRD9 | |
| SCHEMBL8027058 | 0.82 | F2 (0.70) | BRPF1BRD1BRPF3BRD4BRD9 | |
| Hydrochloric Acid SCHEMBL8026996 | 0.81 | F2 (0.69) | BRPF1BRD1BRPF3BRD4BRD9 | |
| SCHEMBL8026334 | 0.81 | F2 (0.55) | BRPF1BRD1BRPF3BRD4BRD9 | |
| SCHEMBL8029978 | 0.80 | F2 (0.60) | BRPF1BRD1BRPF3BRD4BRD9 | |
| SCHEMBL7981348 | 0.80 | BRPF1 (0.56) | BRPF1BRD1BRPF3BRD4BRD9 | |
| SCHEMBL6637025 | 0.77 | PAX8 (0.64) | BRPF1BRD1BRPF3BRD4BRD9 | |
| SCHEMBL8026550 | 0.77 | F2 (0.73) | BRPF1BRD1BRPF3BRD4BRD9 | |
| SCHEMBL8017541 | 0.77 | F2 (0.72) | BRPF1BRD1BRPF3BRD4BRD9 | |
| SCHEMBL8030047 | 0.76 | KMT2A (0.46) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060166-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | Boehringer Ingelheim Pharma KG (DE) | 2000-12-20 | — | — | EP | disclosed |
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |
| WO-1999040072-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-08-12 | — | — | WO | disclosed |