Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6632565 | 0.87 | KMT2A (0.45) | KMT2ACYP2A6TRPA1ALB | |
| SCHEMBL8016775 | 0.82 | BRPF1 (0.41) | KMT2AIDH1CYP2A6LOXL2 | |
| SCHEMBL8801682 | 0.80 | SLC5A2 (0.44) | KMT2ASLC5A2 | |
| SCHEMBL8032940 | 0.77 | KCNJ1 (0.48) | KMT2AIDH1 | |
| SCHEMBL8801466 | 0.77 | SLC5A2 (0.45) | SLC5A2 | |
| SCHEMBL28274303 | 0.74 | KMT2A (0.67) | KMT2ATRPA1ALB | |
| SCHEMBL1092961 | 0.73 | KDM1A (0.55) | KMT2A | |
| SCHEMBL8016504 | 0.72 | BRPF1 (0.52) | — | |
| SCHEMBL1882418 | 0.70 | KMT2A (0.50) | KMT2A | |
| SCHEMBL6636737 | 0.70 | ALB (0.61) | KMT2ATRPA1ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060166-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | Boehringer Ingelheim Pharma KG (DE) | 2000-12-20 | — | — | EP | disclosed |
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |
| WO-1999040072-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-08-12 | — | — | WO | disclosed |